The 31-year-old will be expected to play a crucial role for Spurs at the Camp Nou on Tuesday

You have to go back May 2013 for the last time Barcelona lost a European match at the Camp Nou, but Tottenham Hotspur will hope to change this on Tuesday night.

Since suffering a 3-0 defeat to Bayern Munich, the La Liga giants have won 26 home games in the Champions League and drawn on just two occasions to Atletico Madrid and Juventus.

It shows the size of the task at hand for Mauricio Pochettino’s team, but Spurs centre back Jan Vertonghen is confident ahead of this week’s crucial clash.

He said: “We definitely have a good chance. The way we are playing now gives us a lot of confidence.

“We have all the quality in the world to beat them. We believe in that and we will try everything.”

Tottenham have won eight of their last nine games in all competitions with the only blot on their recent copybook a 4-2 reverse at Arsenal on December 2.

During this period, Spurs have achieved victories away to rivals West Ham United, Wolverhampton Wanderers, Crystal Palace and most recently Leicester City at the weekend following an impressive 2-0 success.

At home, they have also seen off PSV, Chelsea, Inter Milan and Southampton to sit third in the Premier League and now second in Group B of the Champions League.

The Lilywhites have already won two must-win European games this season, but they were both at Wembley Stadium.

An 89th-minute winner from forward Harry Kane inspired a 2-1 triumph over PSV on November 6 and Christian Eriksen’s late strike saw off Inter on November 28 by a 1-0 scoreline in the capital.

This would be their biggest victory of all, however, but the odds remain firmly against them with injuries piling up.

Serge Aurier, Kieran Trippier, Juan Foyth, Davinson Sanchez, Mousa Dembele, Victor Wanyama and Erik Lamela could all be missing when Spurs line up to face the La Liga champions knowing they must match Inter’s result at home to PSV.

Vertonghen added: “We want to stay in every competition for as long as possible and we are still in all of them, so hopefully we can keep going.”