Boss Mauricio Pochettino will have two key attackers missing for the London derby

Spurs will be without forward Harry Kane for Sunday’s fixture away to Premier League strugglers Fulham.

The Tottenham Hotspur vice-captain suffered a blow to his ankle in the closing stages of the 1-0 defeat to Manchester United last weekend and is not set to come back until early March.

He had a scan on the injury on Tuesday and Spurs will be without their top goalscorer for the foreseeable future due to damaged ligaments.

The Lilywhites hitman is not the only attacker missing for the trip to Fulham with Heung-min Son unavailable now too.

United was his last game for Spurs before he jetted off to link up with South Korea for the Asian Cup.

If his country makes it all the way to the final, Son will miss games away to Fulham, Chelsea and Crystal Palace plus clashes with Watford and Newcastle United at home.

With Kane and Son out of action, boss Pochettino may turn to Fernando Llorente, who scored a hat-trick in his last start at Tranmere Rovers.

He last started a Premier League match over a year ago, though, in the win at Swansea City on January 2 – a game where he scored the opener.

Alternatively, Spurs could try one of Dele Alli or Erik Lamela up top with Brazilian Lucas Moura still not 100 per cent fit after a knee injury.

On Monday, he told fans on Twitter: “The knock was strong, it is still painful. I am doing full time treatment to be ready as soon as possible.”

Elsewhere, the news seems more positive regarding Eric Dier, who has not featured for Spurs since December 8.

He returned to training last week and will hope to either play a part at Fulham or be back for the trip to Chelsea in the League Cup (January 24).

Victor Wanyama is slowly working his way back to full fitness too and Pochettino will be desperate for him to return in the near future.

Moussa Sissoko suffered a groin injury during Sunday’s defeat to United and had to be replaced, but it is believed to be a small issue.

Nevertheless, Wanyama and Dier coming back into contention over the next few days would be a welcome boost for Spurs.