Mauricio Pochettino will try to make changes to his back four for the visit of Sean Dyche's side
The Spurs defender recovered from his early mistake to make what would prove to be a key block in the second half
The 21-year-old signed a new five-year deal with Spurs on Monday and will now start away to Barcelona
The 31-year-old will be expected to play a crucial role for Spurs at the Camp Nou on Tuesday
The Argentine defender has recently forced his way into Mauricio Pochettino's starting XI
Spurs will be without Jan Vertonghen, Davinson Sanchez, Victor Wanyama, Mousa Demble and Erik Lamela for the visit of Southampton
Arsenal are expected to make up to ten changes against Spurs for the 195th North London at the Emirates on Sunday afternoon.
Mauricio Pochettino must decide whether Jan Vertonghen is ready to play back-to-back games so soon after his hamstring injury
Danny Rose is also back in training for Tottenham Hotspur ahead of Wednesday's European clash with Inter Milan
Mauricio Pochettino accepts he is pushing his Tottenham squad to the limit as he counts of the cost of their World Cup exploits.
Tottenham manager Mauricio Pochettino says the club is working hard to get Christian Eriksen to commit his future to the club.
Premier League: Crystal Palace 0 Tottenham Hotspur 1
Tottenham Hotspur manager Mauricio Pochettino understands fans frustration as they jeered in the 62nd minute when he brought off Lucas Moura in their 2-1 Champions League win against PSV.
Spurs have received criticism for a lack of depth, but Mauricio Pochettino used 22 different players in the last two games and most impressed
Premier League: Wolverhampton Wanderers 2 Tottenham Hotspur 3
Spurs conceded early against Manchester City, but Argentinian Pochettino was impressed with their response
Erik Lamela fired over for Tottenham Hotspur with 10 minutes left and Man City boss Pep Guardiola blamed the pitch for the miss
While individuals could be blamed for Tottenham's struggles in Europe, collectively the team have not been good enough
A look at how some of Tottenham Hotspur's players fared while on international duty over the weekend
A look at how some of Tottenham Hotspur's players fared while on international duty this week
The Tottenham Hotspur forward discusses the upcoming UEFA Nations League games and Harry Winks' inclusion in the England squad
The Lilywhites are joint-bottom with no points while Barcelona and Inter Milan both have six each after two games in Group B
Champions League Group B: Tottenham Hotspur 2 Barcelona 4
The Lilywhites will be without Aurier, Vertonghen, Dembele, Alli and Eriksen for this week's Champions League Group B fixture
Premier League: Huddersfield Town 0 Tottenham Hotspur 2
Mauricio Pochettino will once again be without some key men this weekend
The Lilywhites ended a three-game losing run with a 2-1 success at Brighton & Hove Albion on Saturday
Premier League: Brighton & Hove Albion 1 Tottenham Hotspur 2
Spurs will take on Inter Milan in a 5.55pm kick-off, but will be missing several key players
The Reds manager labelled their display at Spurs as their 'best game of the season'
Several Spurs players were involved in international matches on Tuesday
The Spurs full-back dismissed any worries about recent form and offered his view on Danny Welbeck's disallowed goal
Various Tottenham players have enjoyed international success over the past few days
The Red Devils boss reflected on the 3-0 defeat to Tottenham Hotspur
The Spurs boss hailed the belief and togetherness of his group after a landmark victory at Manchester United
The Spurs boss has challenged his squad ahead of Monday's fixture away to Manchester United
The former Burnley full-back enjoyed a fantastic tournament in Russia and scored for his club last weekend
The Argentinean discussed the mentality of the squad and the importance of Harry Kane's August goal
The former Spurs striker enjoyed a two-and-a-half year spell at White Hart Lane
The 50-year-old reflected on the Premier League loss to Tottenham Hotspur at Wembley Stadium
Tottenham Hotspur's manager spoke for five minutes and 12 seconds uninterrupted towards the end of his press conference on Saturday
Tottenham Hotspur manager Mauricio Pochettino was pleased with his players in their 3-1 victory against Fulham but believes there is still plenty to improve on despite winning both of their Premier League matches so far.
Premier League: Tottenham Hotspur 3 Fulham 1
The Argentinean is happy with his squad heading into the new Premier League season
Tottenham Hotspur are set to be without a number of players for Saturday's opener at Newcastle United
The Lilywhites will have to field another weakened side for the final game in the International Champions Cup
Fernando Llorente, Lucas Moura, Erik Lamela and Serge Aurier all caught the eye during Spurs' 4-1 win over AS Roma
Toby Alderweireld played his part to deny five of his Spurs team-mates a chance of finishing third in Russia
So, England finished fourth at the World Cup finals in Russia.
Toby Alderweireld, Jan Vertonghen and Mousa Dembele couldn't hide their disappointment after Tuesday's loss to France